Lisinopril is about the most popular drug in the pharmacy. This ACE (angiotensin converting enzyme) inhibitor is swallowed by over 20 million hypertensive Americans every day. Over 110,000,000 bottles of lisinopril are dispensed each year. Now that so many ARBs (angiotensin receptor blockers) have been recalled because of nitrosamine contamination, we suspect a lot more people will be taking lisinopril. Anyone who is taking lisinopril needs to be very cautious about taking extra potassium. This reader wants to know how ACE inhibitors like lisinopril interact with other nutrients.

Taking Lisinopril? Avoid Potassium! Consider Zinc!

We fear that most people do not take time to ask their doctors or pharmacists about drug interactions. If someone is taking lisinopril that can be a dangerous, or even a deadly oversight.

Q. I take lisinopil for high blood pressure. I know I should avoid extra potassium. Are there any other vitamins or minerals I should watch out for?

A. Potassium is the most important. Too much potassium can be just as dangerous as too little, so you should be careful not to take supplemental potassium or use potassium-based salt substitutes.

What Happens if Potassium Goes Too High?

In the worst case, death can result. That’s because hyperkalemia (excessive potassium) can cause cardiac arrest. In plain talk, your heart stops beating regularly and the grim reaper is not far behind.

Other symptoms of too much potassium include fatigue, irregular heart rhythms, weakness, breathing difficulties, tingling or numbness in fingers, feet or lips, slow heart rate and mental confusion.

You can learn more about interactions that can lead to excess levels of potassium when taking lisinopril at these links:

A Deadly Drug Interaction Often Ignored by Doctors and Pharmacists

Will Your Antibiotic Interact with Your Blood Pressure Pill?

Lisinopril and Too Little Zinc:

We hope that doctors and pharmacists warn their patients taking lisinopril (and other ACEis) to avoid extra potassium. This is an interaction that is taught in medical and pharmacy schools. It is also programmed into the computers that doctors use to prescribe and pharmacists use to dispense. 

We suspect that most health professionals are unaware of the connection between blood pressure pills like lisinopril and low levels of zinc. Research has shown that ACE inhibitors can deplete the body of zinc (Nutrients, Sep. 11, 2018). If there is a diuretic on board it could be even worse. 

Zinc plays an essential role in immunity. It simulates T cells. They play a central role in combatting viral and bacterial infections. Older people who are deficient in zinc are at greater risk of coming down with pneumonia, especially if they are in a nursing home.

Please ask your doctor to monitor your zinc status so you will know if you need a supplement.

Which Vitamins and Minerals Should You Be Taking?

If you would like to know more about which supplements you should be taking to counteract medication depletion, we highly recommend a book by Dr. Low Dog titled Fortify Your LIFE: Your Guide to Vitamins, Minerals and More.

We have the only affordable paperback edition available. We think it is the best and most up-to-date analysis about which dietary supplements are essential for good health. Dr. Low Dog makes sense out of what has been total confusion. Here is a link to her book, Fortify Your LIFE.

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